How Does Age Affect Fertility in the Older Woman?

Many fertility specialists characterize a more aged lady as one who is over 35 years if planning to conceive they should not delay their pregnancy planning more A woman’s fertility doesn’t tumble off at a specific age, however begins declining step by step after the age of 30. After 35, the drop is genuinely sensational; and after 38, it’s considerably more so. Be that as it may, there is no enchantment number at which richness vanishes and this decrease is a dynamic irreversible procedure.

Previously, it was accepted that as the lady becomes older, her whole reproductive framework began coming up short. In any case, today we realize that the uterus and the fallopian tubes remain moderately unaffected by age; and that the explanation behind the decrease in richness is the reduced number of eggs left in the ovary. Every girl is born with a finite number of eggs, and their number progressively declines with age. A measure of the remaining number of eggs in the ovary is called the “ovarian reserve”; and as the woman ages, her ovarian reserve gets depleted. The infertility specialist is really not interested in the woman’s calendar (or chronological age), but rather her biological age – or how many eggs are left in her ovaries.

What are The Tests for Measuring Ovarian Reserve?

Various tests have been described, to measure the ovarian reserve, so that we can determine which patients are good candidates for treatment. These tests are based on measuring the level of the FSH level in the blood; and include a basal (day 3) FSH level. A high level suggests poor ovarian reserve; and a very high level is diagnostic of ovarian failure. A test that can provide earlier evidence of declining ovarian function is the clomiphene citrate challenge test (CCCT). This is similar to a ” stress test ” of the ovary; and involves measuring a basal Day 3 FSH level; and a Day 10 FSH level , after administering 100 mg of clomiphene citrate from Day 5 to Day 9. If the sum of the FSH levels is more than 25, then this suggests poor ovarian function, and predicts that the woman is likely to have a poor ovarian response (she will most probably grow few eggs, of poor quality) when super ovulated. Another test which has been recently developed is the measurement of the level of the hormone, inhibin B, in the blood. Low levels of inhibin B ( which are produced by”good” follicles) suggests a poor ovarian reserve. However, just because a test result is normal does not mean that the quality or number of the eggs will be good – the final proof of the pudding is always in the eating!

The menopause is easy to define, because it is the point at which the menses cease, and at this time the eggs in the ovaries are finally depleted. However, the quality of eggs starts declining well before the menopause starts. Some specialists calls this the “oopause” – the time period before the menopause, during which fertility progressively declines because of deterioration in the quality of the eggs. This can manifest itself in many ways, some of which are extremely subtle, which is why the oopause can be so hard to identify. Initially, these women may present as having recurrent miscarriages, and then as having “unexplained infertility”. While the number of eggs they grow seems fine initially, they do poorly in the IVF lab. Initially they may have unexplained implantation failure of apparently satisfactory embryos; and later, poor quality embryos; and then failure of fertilization.

What is The Relationship between Infertility and The Midlife Crisis?

Infertility and the Midlife Crisis
Many women in their late 30s early 40s have postponed marriage or childbearing to obtain their education, establish themselves in careers, and become financially secure. These aspirations frequently have worked against the decision to have children. The passage of time, however, alters the way many women feel about motherhood by changing their perceptions about themselves as well as about the world around them. Additionally these changes may also have to do with having a new sense of maturity as well as a feeling of accomplishment. Thus, as women-and men-feel more secure about themselves, their feelings and ideas about children and parenthood may also change.

As a couple moves into midlife, they must also begin recognizing and coming to terms with their own mortality. For many, parenthood is a part of successfully completing an important stage in life. As couples begin to see and understand the passage of their own lives, the need to pass along life experiences to new generations enhances the meaning of life.

Men and women in midlife, who have made the decision to have children, may find to their dismay that they are frequently thwarted by the inability to conceive or by recurrent miscarriages. For women, the realities of the biologic clock cannot be overlooked. At this point, many couples are faced with dual crises which can compound their problems -infertility, as well as a midlife crisis – the developmental life changes that normally occur in the middle years. This is why we suggest that women who are more than 30 and who wish to postpone childbearing should get their FSH levels checked on Day 3 of their cycle. This is a simple blood test which allows the doctor to check your ovarian reserve (the quantity and quality of the eggs in your ovaries). A high level suggests poor ovarian reserve and should be a wake-up alarm that your biological clock is ticking away rapidly. It’s important that this test should be done in a reliable laboratory.

As women reach menopause, they begin to realize that the option of conceiving and bearing a child is closed to them. Just as the array of other life choices begins to narrow, the loss of this ability to choose to have a child can result in sadness and deep disappointment. The realization of this “missed opportunity” can also lead to self-recrimination and depression.

How Can Donor Eggs Help the Older Infertile Woman?

A very effective option for older woman whose own eggs do not grow well is that of using donor eggs or donor embryos. However, this is obviously a very sensitive emotional issue, and each couple needs to make their own decision. While using donor eggs and embryos does dramatically improve pregnancy rates, it is often an option many couples find hard to come to terms with.

It is also becoming increasingly difficult to find suitable egg donors. Finding altruistic egg donors is an uphill task for most women, because they are often very reluctant to ask for help, since this would involve telling others about their problem.

Support groups like NEEDS (National Egg and Embryo Donation Society) in the UK have been very helpful in motivating voluntary egg donors by creating public awareness of the need for healthy young women to donate their eggs. Clinics have also adopted various approaches to help resolve this problem. Some large clinics run successful anonymous egg donation programs; others use known egg donors (either paid or unpaid); and others encourage their patients to share their supernumerary eggs (often for a financial consideration) with other patients.

An exciting option for the future may be that of egg banking. A lot of research is being focused on developing more efficient methods to cryopreserve and store eggs. If this becomes clinically practicable, then it may become possible to freeze a woman’s eggs or ovarian tissue when she is young, and store these for her in liquid nitrogen at -196 C, so that she can use her own “young” eggs in the future, whenever she decides to start her family!

The Bottom Line –

As ladies and men age, their capability to have kids diminishes, in spite of the fact that precisely when this begins to happen can fluctuate among people.

Over a populace, ladies more youthful than 35 and men more youthful than 40 have a superior possibility of having a kid than individuals who are more established. This is valid for normal pregnancies and for pregnancies considered through helped regenerative medications, for example, IVF (in-vitro preparation).

The role of Age in Woman’s fertility 

A lady is brought into the world with all the eggs she will ever have. As she ages her eggs age with her and their number and quality diminishes after some time. This is the reason her opportunity of having a child additionally diminishes after some time, particularly for ladies more seasoned than 35 years old.

Therefore it is hard to attain success in women who have crossed 35 age. Women with older age can easily have their baby but the woman might not get positive result with her own-eggs (because of her diminished ovarian reserve or poor egg quality). She can select IVF treatment with donor egg from our centre provided by We Care IVF Surrogacy.

Age and sperm

Men who are younger the age of 40 have a superior possibility of impregnating their partner than those older than 40. The quality of the sperm men produce appears to decay as they get of age.

Most men make a numerous new sperm consistently, however this is the fact that men who are above 40 have less motile and healthy sperm. The measure of semen (the liquid that contains sperm) and sperm motility (capacity to move towards an egg) decline ceaselessly between the ages of 20 and 80.


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