PGD In India: Cost, Success Rate & Best Clinics
India remains a globally recognised destination for different fertility treatments. For getting an affordable PGD (Preimplantation Genetic Diagnosis) treatment PGD in India. This is a treatment which helps in diagnosing genetic disorders. The tests are before the implantation to have a healthy baby.
Embryos are tested before implantation, it is done during IVF (In Vitro Fertilization). There is a constant fear in couples going for IVF treatments, if the treatment will be successful or not. They keep stressing about this which makes couples sceptical about this procedure. But there are multiple treatments which can help solve this problem even before surgery.
PGD (Preimplantation Genetic Diagnosis) helps in recognizing if there are any genetic disorders by testing embryos at the five to six-day-old blastocyst stage, and it helps in selecting healthy embryos which eventually helps in getting success results. Choose We Care IVF Surrogacy for PGD in India.
How Is PGD done In India?
PGD (Preimplantation Genetic Diagnosis) is a test performed during IVF (In Vitro Fertilisation), it is the part of the diagnosis which is done before the embryo implantation and this test is done for ensuring if the patient is dealing with any genetic disorder. The test is done with the embryos, which are five to six days old, in the blastocyst stage for selecting the healthy embryos for implantation.
Procedure Of Preimplantation Genetic Diagnosis(PGD) In India
- Ovaries are stimulated for the production of eggs.
- The next stage is harvesting eggs after ovarian stimulation.
- Then they are fertilised by sperm and egg.
- Genetic screening, such as PCR or FISH are done.
- Transferring only healthy embryos to reduce the chances of miscarriage.
- Unused embryos are used for future pregnancy.
Types Of PGD / PGT
PGT-A (Preimplantation Genetic Testing for Aneuploidy)
- This is treatment which tests and analyses for the required number of chromosomes.
- It is done before the implantation selecting a healthy embryo.
- It is conducted when the embryo is at the blastocyst stage.
- The number of embryos has to be 46 which assures success.
PGT-M (Preimplantation Genetic Testing for Monogenic/Single Gene Disorders)
- This test is done for checking inherited genetic disorders.
- Helps in preventing the transmission of genetic diseases.
- It is ideal for the couples who have a history of genetic disorders.
- Helps in selecting healthy embryos for implantation.
PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements)
- This test is done for checking the abnormalities of chromosomes.
- This helps in prevention of transmission of genetic disorders.
- It tests for structural rearrangements in embryos.
- Mostly the couples are not even aware of these tests.
How Effective Is Preimplantation Genetic Diagnosis (PGD) In India?
PGD (Preimplantation Genetic Diagnosis) is a treatment which helps test genetic disorders before the implantation. Therefore, test considered to be an effective method to improve the chances of pregnancy. It yields a high success rate in India. With relatively improved outcomes in women aged below 35.
Genetic screening allows selecting the embryo which has the required number of chromosomes. This helps in increasing fertility and implantation rates helps in reducing the risk of failure in pregnancy. And hence, the success of PGD depends on the age of the woman, the egg, the quality of the embryo, and the number present for testing.
| Factor | Category | Success Rate (PGD + IVF) | Impact on Outcome |
|---|---|---|---|
| Female Age | < 35 years | 60% – 85% | Highest implantation and pregnancy rates |
| 35 – 40 years | 45% – 65% | Moderate decline in egg quality | |
| > 40 years | 25% – 45% | Significant drop in success | |
| Embryo Quality | Genetically normal (euploid) | 60% – 75% | Strong implantation potential |
| Abnormal (aneuploid) | ~0% | Usually not transferred | |
| Number of Embryos Available | High (≥5 embryos) | 65% – 80% | The chances of the selection of embryos get better |
| Low (<3 embryos) | 30% – 50% | A lower number of embryos limits the selection and reduces success | |
| Clinical Scenario | Recurrent IVF failure | 50% – 70% | Per cycle chances improve |
| Recurrent miscarriage | 55% – 75% | The risk of miscarriage reduces significantly. | |
| Genetic disorder cases | 60% – 80% | The chances of disease transfer reduce | |
| IVF Centre Quality | Advanced lab + experienced team | 60% – 80% | Embryo survival and higher accuracy |
| Average setup | 40% – 60% | The consistency in outcomes lowers. | |
| Biopsy Technique | Blastocyst biopsy (Day 5) | 60% – 75% | Accrues a higher success |
| Cleavage-stage biopsy (Day 3) | 40% – 55% | A lower accuracy |
What is the best-case scenario?
The patient should be young has high-quality embryos, treatment within a technologically advanced lab, pregnancy rates reach nearly 80-85% per cycle.
What are challenging cases?
Success rates decrease substantially when the patient is of an advanced age and a limited number of embryos for genetic analysis. The success rates come around 25% and 45% per cycle.
Difference Between PGD And PGS (PGT-A)
Genetic testing is a great discovery in the field of medicine; it has evolved over the years and has become a procedure which has improved outcomes and helps in preventing the passing on of genetic disorders. The chances of inheriting genetic diseases from generations before decrease. The two common terms are PGD (Preimplantation Genetic Diagnosis) and PGS (Preimplantation Genetic Screening), now called PGT-A (Preimplantation Genetic Testing for Aneuploidy).
PGD (Preimplantation Genetic Diagnosis)
A genetic test for recognising inherited disorders that is done before implantation. It is prescribed to both male and female partners since both partners can be carriers of any genetic conditions.
- This method detects single-gene mutations or chromosomal abnormalities.
- Detects thalassemia, cystic fibrosis, sickle cell anaemia, or Huntington’s disease
PGS (Preimplantation Genetic Screening) or PGT-A (Preimplantation Genetic Testing for Aneuploidy)
PGD, now referred to as PGT-A, is a screening method that tests for chromosomal number abnormalities (aneuploidy). It does not check for any particular disease, but if the embryo has the correct number chromosomes(46).
- Selecting an embryo with the correct number of embryos improves the success rate
- The chances of miscarriage reduce with advanced maternal age.
Key Difference Between PGD and PGS (PGT-A)
| Aspect | PGD (Preimplantation Genetic Diagnosis) | PGS / PGT-A (Preimplantation Genetic Screening) |
|---|---|---|
| Purpose | Helps in diagnosing genetic diseases | This procedure detects chromosomal abnormalities |
| Who Needs It? | Couples who have already been diagnosed with genetic disorder | The chances of miscarriage increases in women with an advanced age |
| Type of Testing | The test done here is single-gene mutation | Screening for number of chromosome |
| Goal | For avoiding genetic disorders. | For selecting the right embryo with right chromosome |
| Accuracy Focus | Disease-specific | Overall chromosomal health |
Cost Comparison Table: PGD Vs PGT-A (PGS) In India
| Cost Component | PGD (Preimplantation Genetic Diagnosis) | PGT-A / PGS (Chromosomal Screening) |
|---|---|---|
| Genetic Testing Cost (batch) | ₹1,50,000 – ₹2,50,000 | ₹1,50,000 – ₹3,00,000 |
| Per Embryo Cost (if charged separately) | ₹5,000 – ₹10,000 per embryo | ₹15,000 – ₹20,000 per embryo |
| IVF + Testing Package (total) | ₹2.7 – ₹4.5 Lakhs | ₹2.5 – ₹4.0 Lakhs |
| With Donor Egg Cycle | ₹4.5 – ₹6.0 Lakhs | ₹4.0 – ₹5.5 Lakhs |
| Genetic Counselling & Setup | ₹25,000 – ₹75,000 | ₹25,000 – ₹75,000 |
| Embryo Freezing & Storage (1 year) | ₹15,000 – ₹40,000 | ₹15,000 – ₹40,000 |
| Medication Cost (IVF cycle) | ₹60,000 – ₹2,00,000 | ₹60,000 – ₹2,00,000 |
| Frozen Embryo Transfer (FET) | ₹60,000 – ₹90,000 | ₹60,000 – ₹90,000 |
PGD remains more expensive than PGT-A since the tests include testing for genetic diseases. PGT-A has a comparatively lower cost since it is done for number of chromosomes. An IVF cycle cost combined with genetic testing is ₹2.5–₹4.5 lakhs in India. The cost is affected by different reasons. It depends on the number of embryos, the kind of technology that has to be used, location of clinic, experience of lab quality and so on.
Success Rate Comparison: PGT-A (PGS) Vs PGD In India
| Parameter | PGD (PGT-M – Genetic Disease Testing) | PGT-A (PGS – Chromosomal Screening) |
|---|---|---|
| Initial Goal | Helps avoiding specific inherited diseases | Select chromosomally normal embryos |
| Rate of Implantation | 45% – 60% | 50% – 70% |
| Rate of pregnancy | 50% – 60% | 55% – 65% |
| Live Birth Rate (per transfer) | 45% – 65% | 50% – 70% |
| miscarriage risk | Moderate (depends on embryo quality) | Lower due to euploid embryo selection |
| Success in Women under 35 yrs | 55% – 70% | 60% – 70% |
| Success in Women over 35 yrs | 35% – 65% | 40% – 60% (better benefit in this group) |
| Average success rate in India | 45% – 65% | 50% – 70% |
Conditions that PGD helps in determining
There are multiple conditions that PGD tests such as Beta Thalassemia Trait.
- Sickle cell anaemia is another genetic disorder that affects hemoglobin.
- Cystic Fibrosis affects respiratory and digestive issues.
- SMA 1 (Spinal Muscular Atrophy Type 1), it is a neuromuscular disorder.
- Tay-Sachs, affects nerve cells and spinal cord.
- Fragile X, causes intellectual disability and autism.
What are the benefits of PGS and PGD?
There are multiple benefits of these procedures. Since the procedure detects the genetic disorder and the right amount of chromosomes. The families which have a history of genetic diseases going for these helps a lot.
- This helps in choosing the best embryos which eventually helps getting a successful IVF.
- The chances of pregnancy with this procedure rises and patients get positive results.
- Adding this to IVF helps give successful results. This is a right financial decision for IVF.
- If there is a history of genetic disorders it might pass. This test helps ascertain the disorder prior to transplantation.
Why choose PGD in India?
- India assures a higher success rate of Preimplantation Genetic Diagnosis (PGD).
- It remains affordable in terms of both accommodation and treatment.
- It offers cost-effective treatments which yield results and high-quality treatment.
- Helps in preventing inherited diseases and the genetic diseases do not get transferred.
- The chances of misscarriage also reduces and you get better results.
- It helps in avoiding transmission of diseases such as Thalassemia, Cystic Fibrosis, Sickle Cell Anemia.
- It is helpful for women who had multiple pregnancy loss.
- Saves time, patients do not require to go for multiple IVF cycles.
Top PGD Clinics In India
| Clinic Name | Location | Estimated PGD Cost (₹) | Typical IVF + PGD Package (₹) |
|---|---|---|---|
| We Care IVF Surrogacy | Delhi / PAN India | ₹1,50,000 – ₹2,50,000 | ₹2.8 – ₹4.5 Lakhs |
| World Fertility Services | PAN India | ₹1,40,000 – ₹2,40,000 | ₹2.7 – ₹4.2 Lakhs |
| Select IVF | Delhi / PAN India | ₹1,50,000 – ₹2,60,000 | ₹2.8 – ₹4.3 Lakhs |
| Go IVF Surrogacy | India (Multiple Cities) | ₹1,30,000 – ₹2,30,000 | ₹2.5 – ₹4.0 Lakhs |
| ACME Fertility | Various Cities | ₹1,40,000 – ₹2,50,000 | ₹2.7 – ₹4.2 Lakhs |
| Kiran Infertility Clinic | Bangalore | ₹1,80,000 – ₹3,00,000 | ₹3.5 – ₹5.5 Lakhs |
| Zoi Fertility | Mumbai | ₹1,70,000 – ₹2,80,000 | ₹3.2 – ₹5.0 Lakhs |
| Mediworld Fertility | Delhi | ₹1,40,000 – ₹2,40,000 | ₹2.7 – ₹4.0 Lakhs |
| Prime Fertility | Gurgaon | ₹1,50,000 – ₹2,50,000 | ₹2.8 – ₹4.2 Lakhs |
| We Care Nidus Fertility | Mumbai | ₹1,60,000 – ₹2,70,000 | ₹3.0 – ₹4.8 Lakhs |
Top 5 IVF Centre In India
Difference Between PGT-A Vs PGT-M
PGT-A was formerly known as PGS and PGT-M which was formerly known as PGD is an advanced treatment that helps selecting the right embryo. PGT-A is done for testing genetic disorders and PGT-M is done for checking the number of chromosomes and helps in choosing the right embryo for implantation.
Who Should Consider Choosing PGD?
There are multiple reasons why you should consider going for PGD in India. It helps in preventing transmission of genetic disorders.
- Women aged over 35 since they are already at a higher risk of transmitting these anomalies.
- Couples who had recurrent failed IVF cycles and PGD improves the chances of pregnancy.
- Families with a history of genetic disorders, PGD prevents the chances of transmission.
- Women who are repeatedly going through recurrent miscarriages.
- PGD lowers the chances of transmission by testing for the right embryo.
- For having a safe and healthy baby for a high success rate.
Why Do International Patients Choose India For PGD?
- Choose India for affordable and safe treatments. We have highly-qualified doctors.
- Here medical visa assistance is available with prompt support.
- Language assistance is also provided which helps patients from abroad.
- India has advanced labs which are well-equipped with modern technology.
- Treatments do not take too much time for completion.
- These treatments are done with a proper diagnosis.
- Everything is planned around the couple’s time.
- Empathetic treatments with professional care.
Top Cities For PGD In India
Best PGD Clinic In India
We Care IVF Surrogacy provides a safe and trusted treatment. We have put years and years of effort into providing a successful treatment. Our medical and non-medical staff work the best. The way the staff treats you also remains very important in considering the best treatment. If you are planning for treatment in India choose We Care IVF Surrogacy.
We use the latest technology in our procedures that assures results and patients stay carefree. This procedure functions best when women go through this procedure when they are under 35. We are one of India’s leading centres. We return patients with successful results.
Tips For Choosing The Right Centre for PGD In India
There are multiple factors you should consider before choosing the best centre in India.
- Search for initial consultation if available online. This helps you get a brief on the whole procedure.
- Carefully decide the location you are planning to come for the treatment. Since the whole procedure takes time and multiple visits and for that you should choose the location that is near the clinic.
- The cost is also a major factor in deciding the clinic for PGD. You should choose the cost which suits you. It should be your own decision and you should accordingly.
- And create a list of 10 best centres for this treatment or check this page for this list. This gives a brief on what you need to choose according to your own requirements.
The Rapid Growth Of Medical Tourism: Rising Demand for PGD in India
Medical tourism is going through evolution and significantly becoming into a powerful global healthcare movement itself, in addition to this it works by rising treatment costs in developed nations, long long waiting times, and increasing awareness of high-quality affordable care in growing destinations. Moreover, countries like India have established themselves at the adapting to this shift and kept themselves at the forefront of this shift, offering advanced medical infrastructure, internationally accredited hospitals, and highly skilled specialists a fraction of the cost seen in the regions the United States or United Kingdom. Whereas, the affordability, accessibility, and quality has made India a preferred destination for patients seeking specialized treatments.
Within this system, reproductive medicine has experienced a significant surge, specifically procedures like Preimplantation Genetic Diagnosis (PGD). PGD is an advanced genetic screening technique it is used during IVF to identify the embryos free from specific genetic disorders before the implantation. In addition, technology has become especially relevant for international patients who are at risk of hereditary conditions or have experienced repeated IVF failures.
Future of Genetic Testing in Fertility Treatments
- The future of genetic testing in the fertility care is shaped by growing advancements in technologies such Next-Generation Sequencing and Artificial Intelligence.
- There are innovations which are making procedures like Preimplantation Genetic Diagnosis (PGD) more easier, efficient, and accessible for treatment.
- The growing techniques in these days are expected to allow comprehensive embryo screening with greater accuracy, enabling clinicians to detect not only the single-gene disorder but also many complex genetic abnormalities.
- This could significantly help in improving an implantation rates and reduce the risks of inherited conditions, marking a shift toward a highly personalized reproductive care.
Looking ahead, genetic testing fertility treatments is likely to moves further the scope of disease prevention into predictive and preventive healthcare. With a deeper insight into embryonic genetics doctors might be able to assess a long-term health risk, in making the way for more informed and right reproductive decisions, that helps. Moreover, in countries like India, where fertility services are rapidly evolving, the integration of advanced genetic tools with affordable treatments models could further make stronger its position in global reproductive medicine. Moreover, as these capabilities expand, taking ethical considerations, regulatory frameworks, and consider use of genetic data will play a crucial role in shaping the future of this field.
What Happens After These Procedures?
- After the PGT-A, PGT-M, PGT-SR is done, a healthy embryo is selected.
- The remaining embryos which are further frozen for future pregnancy.
- After five to seven days they are implanted in the uterus.
- A few times hysteroscopy is also performed for improving implantation.
What Factors To Consider Before PGD?
There are multiple factors involved to consider before PGD.
- Financial planning prior to the test has to be an essential factor.
- Location is also a major factor to consider before planning.
- Choosing location prior gives the ease throughout the procedure.
- Hospitals too are an important factor that you should research prior.
- Specialists who are experienced in their discipline also help for this.
- Check for testimonials of patients; it gives brief information about the treatments.
- Online consultation also helps planning the treatment better.
A Step-By-Step Detailed Procedure For PGD Testing
As a matter of fact, fertility treatments remain a complex process which stresses couples and they remain curious about the whole procedure. The whole procedure is enlisted below to provide an in-depth analysis of the whole procedure since it’s not just the PGD but this is paired with IVF.
1. Initial Consultation and Diagnosis
First of all, comes Initial Consultation and diagnosis, which remains the initial and major part of the whole IVF-PGD procedure. It involves the diagnosis and consultation which helps guide through the procedure. Medical history is checked in this.
2. Ovarian Stimulation
Then Ovarian Stimulation is performed for stimulating ovaries involving medication for this procedure. This takes 11 to 14 days for the completion of this procedure. Keep track of every stage carefully. Carefully scheduling all the stages makes the whole procedure more systematic.
3. Egg Retrieval
Further Egg retrieval is performed where the mature eggs are retrieved for fertilization. It is retrieved through with the help of a thin needle to collect eggs from the ovaries. This helps in collecting eggs.
4. Sperm Collection
Then further sperm collection is undertaken where sperm is collected for further procedures. The fertilization is done under observation and in a laboratory.
5. Embryo Culture
Embryo culture is the next step in the whole procedure which takes almost three to five days for development of the fertilized eggs into an embryo.
6. Embryo Biopsy
Embryo biopsy, where few cells are removed from embryo for genetic testing. It is done for the procedure where genetic testing of the embryo is required for genetic testing.
7. Genetic Testing
The stage after embryo biopsy comes, genetic testing, where genetic abnormalities and chromosomal structure and number is tested.
8. Embryo Transfer
The last step in this procedure comes is embryo transfer where the healthy embryo is implanted in the uterus by using a catheter.
Lifestyle Changes Before Going For Treatment
- Lifestyle changes work best when you do it before any treatment, especially before IVF.
- Before going for IVF this procedure, it is suggested that you should fix your lifestyle.
- Lifestyle choices such as drinking alcohol and smoking affects any medical treatment.
- Choose a healthy lifestyle that improves overall health and helps for the procedure.
- Physical exercises help a lot in improving one’s overall health.
- Not only does the physical but the mental health too is very important.
- An improved nutritional diet helps improve overall health.
- Fix sleep cycles, taking 7 to 9 hours is essential before treatment.
Is PGD In India Worth Going Through?
India has become a global hub for fertility treatments. It remains a top choice for patients coming from abroad for treatments. Since, India stays a country which has won an international recognition over the years. People from all over the world come for treatment here. Since India facilitates advance technology, safe treatments and empathetic care which builds trust and assures results.
| Factor | Is PGD in India Worth It? | Key Insight | |
|---|---|---|---|
| 💰 | Cost | Yes | In stays an affordable option |
| 📈 | Success Rates | Yes | Helps in improving chances of pregnancy. |
| 🔬 | Technology & Expertise | Yes | Advanced labs and highly-skilled specialists |
| 🧬 | Genetic Screening Benefit | Yes | Helps in preventing inherited disorders |
| ⚠️ | Emotional & Physical Load | Should be considered before any treatment | Involves IVF process, can be demanding |
| 🗺️ | Accessibility | Yes | It is available in multiple cities. And tier 1 cities are chosen by many |
PGD in India is worth going for for the couples who have a medical history for IVF failure. But once considering these aspects are also important.
Legal and Ethical Guidelines in India
Preimplantation Genetic Diagnosis (PGD) in India works within a systematic regulatory which ensures proper functioning of the procedure and ethical structure intended to ensure use of reproductive technologies. Clinics proving PGD must abide by with the Indian Council of Medical Research guidelines and are regulated under the Assisted Reproductive Technology (Regulation) Act, 2021. Frameworks order proper licensing of fertility clinics, standardized laboratory practices, and highly-qualified doctors to maintain safety and transparency in genetic testing and IVF procedures.
An important legal restriction comes from the Pre-Conception and Pre-Natal Diagnostic Techniques (PCPNDT) Act, 1994, it restricts the application of PGD or any genetic testing for sex selection.
Clinics make sure that PGD is conducted only for identifying genetic abnormalities or inherited disorders, not for non-medical preferences.
Therefore, Breach of this act can result into to serious penalties, including cancellation of licenses and legal action.
Guiding patients for embryo selection is important, this helps them make the decision. Medical professionals are required to follow certain guidelines and abide by rules. Informing patients about the whole procedure is also mandatory. Major discussions has been around the PGD in India.
Ethically, PGD raises major requirements around choosing embryo and genetic intervention. Additionally, Medical professionals are required to abide to principles of taking consent before the treatment, ensuring that couples completely have a knowledge and understand the procedure, its restrictions, and results.
Transparency in communication, privacy of genetic information, and client-centred counselling are important ethical responsibilities. Patients should be only are required to be guided, not controlled and convinced when making decisions about embryo selection or continuation of treatment.
Moreover, there are continuous discussions in India around the broader results of genetic testing, containing concerns about “designer babies,” equal access, and socio-cultural sensitivities. As PGD continues to evolve, sustaining a balance between technological advancement and ethical norms stays important. When performed within the legal boundaries and ethical norms, PGD can be a safe option for couples searching for preventing genetic disorders help them building a healthy family.
Conclusion
Preimplantation Genetic Diagnosis (PGD) in India has surfaced as a reliable and accessible choice for couples seeking to reduce the risk of inherited genetic disorders while improving the possibility of a healthy pregnancy. With the advanced fertility technologies, experienced specialists, and relatively affordable costs, India presents a strong balance of quality and value in reproductive care.