Comprehensive Detail about Assisted hatching

Have you ever heard about the term of Assisted Hatching? Okay, if you haven’t ever been into fertility treatment, especially IVF then you might not have any information about this term. This term is associated with IVF treatment (one of the most preferred and chosen fertility treatment).

Since we all know that IVF treatment is accomplished by many ways based on the couple’s infertility type, such as IVF with third-party assistance, IVF with surgical sperm aspiration, and so on. There is one advanced technique, which, when combined with IVF, increases the chance of successful pregnancy, refer as Assisted Hatching in India. This technique helps the embryo to attach into the uterine wall or in the recipient’s womb.

Given below, there is proper information about Assisted hatching technique in India.

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    What is Assisted Hatching in India?

    You must have the basic information about conventional IVF treatment; even if you don’t or want to read a concise description about it then here you are –

    IVF includes multiple procedures involving both – man and the woman in the couple, but majorly the role of the female partner is there. The female is provided fertility medication and regular hormonal injection (for 10 to 14 days) during the first step of IVF. These medications are given to produce multiple eggs from the female’s ovaries at the time of maturity. The female patient pays a few visits in between these days for ultrasounds and blood hormonal tests. Expert investigates the stage of oocytes (eggs) and when eggs are ready to retrieve. On the given date by the expert, the specialist collects the eggs by using a hollow-needle. These eggs are then kept next to the sperm (in the petri dish) for natural fertilization. Once the sperm gets penetrated the egg’s wall, fertilization is nearly accomplished.

    Now if talking, about Assisted hatching in India, the work-role begins here once the embryos are formed.

    Assisted hatching is a laboratory technique which helps IVF or ICSI-created embryos to hatch. During this method, the IVF specialist creates a small hole in the zona pellucida of the embryos – mechanically, chemically or by using a laser – to allow the embryo to ‘hatch out’ through the treated area.

    The fertility team of We Care IVF Surrogacy uses a directional fibre-optic laser system to make a fissure in the zona safely and swiftly. Assisted hatching is the process, which is always carried out just before the fertilized eggs or embryos are transferred into the recipient’s womb or uterus.

    Who should be treated with Assisted Hatching?

    The most commonly used indications for assisted hatching with an in vitro fertilization case are:

    • Age factor – the female partner is older than 37
    • Egg quantity and quality factor – cases in which the woman’s day three follicle-stimulating hormone (FSH) level is elevated, or with a low AMH level or low antral follicle count
    • Embryo quality factor – cases with poor quality embryos (excessive fragmentation or slow rates of cell division)
    • Zona factor – cases with embryos that have a thick outer shell (zona pellucida)
    • Previous IVF failure – cases that have had one or more previous failed IVF cycles

    In our IVF clinic, we use assisted hatching on just about all cases – because we think it increases the pregnancy and delivery rates.

    How is assisted hatching performed using acid Tyrode’s solution?

    • The embryo is held with a specialized holding pipette
    • A very delicate, hollow needle is used to expel the acidic solution against the outer “shell” (zona pellucida) of the embryo
    • A small hole is made in the shell by digesting it with the acidic solution
    • The embryo is then washed and put back in culture in the incubator
    • The embryo transfer procedure is done shortly after the hatching procedure.
    • Embryo transfer places the embryos in the uterus where they will hopefully implant and develop to result in a birth.


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      Pregnancy rates using Assisted Hatching

      Pregnancy rates for in vitro fertilization procedures with assisted hatching have been shown in some published studies to be higher than for IVF without hatching. There is an improvement in the rate of embryo implantation and pregnancy in our IVF clinic with the use of assisted hatching. Apparently, this benefit is not seen in all IVF programs.

      It is possible to damage embryos with hatching and lower the pregnancy rates. Therefore, it is essential that if assisted hatching is done, it must be expertly performed by adequately trained embryologists. You need to select the IVF centre for Assisted Hatching in India after doing a well-research and analysing each aspect about that centre such as the experience count of the embryologist, IVF specialist, clinic’s success rate of IVF with Assisted Hatching and so on.

      The actual pregnancy and live birth rates seen in an individual IVF center will vary according to the hatching technique used, the overall quality of the laboratory, the skill of the individual performing the hatching, the embryo transfer skills of the physician, and other factors.

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      Disclaimer: Under the pre-Conception and Prenatal Diagnostic Techniques (PCPNDT) Act, 1994, prenatal sex determination is banned in India. No test or treatment for sex selection, sex determination, gender selection, gender determination is done in India.

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